MAP2K6 anticorps
Aperçu rapide pour MAP2K6 anticorps (ABIN7223626)
Antigène
Voir toutes MAP2K6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MEK-6 Polyclonal Antibody
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Specificité
- MEK-6 Polyclonal Antibody detects endogenous levels of MEK-6 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human MEK-6 around the non-phosphorylation site of S207
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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Autre désignation
- MEK-6
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Sujet
- Rabbit Anti-MEK-6 Polyclonal Antibody,MAP2K6, MEK6, MKK6, PRKMK6, SKK3, Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3, SAPKK3,MAP2K6 (mitogen-activated protein kinase kinase 6) encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, MAP2K6 is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.,Dual specificity mitogen-activated protein kinase kinase 6
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Poids moléculaire
- observerd band 39kDa
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ID gène
- 5608
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UniProt
- P52564
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Pathways
- Signalisation MAPK, Signalisation TLR, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Antigène
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