Neuregulin 1 anticorps (AA 1-80)

N° du produit ABIN7221488

L’anticorps Lapin Polyclonal anti-Neuregulin 1 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter Neuregulin 1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Neuregulin 1 anticorps (AA 1-80) (ABIN7221488)

Antigène: Neuregulin 1 (NRG1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Neuregulin 1 anticorps

Épitope: AA 1-80

Fonction: Neuregulin-1 SMDF Polyclonal Antibody

Specificité: Neuregulin-1 SMDF Polyclonal Antibody detects endogenous levels of Neuregulin-1 SMDF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human Neuregulin-1 SMDF at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: Neuregulin-1 SMDF

Sujet: Rabbit Anti-Neuregulin-1 SMDF Polyclonal Antibody,Pro-neuregulin-1 membrane-bound isoform, Pro-NRG1, NRG1, GGF, HGL, HRGA, NDF, SMDF,The neuregulin 1 encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).,Pro-neuregulin-1 membrane-bound isoform

Poids moléculaire: observerd band 44kDa

ID gène: 3084

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation