PIAS3 anticorps (AA 10-90)
Aperçu rapide pour PIAS3 anticorps (AA 10-90) (ABIN7216554)
Antigène
Voir toutes PIAS3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 10-90
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Fonction
- PIAS 3 Polyclonal Antibody
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Specificité
- PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the N-terminal region of human PIAS 3 at AA range: 10-90
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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Autre désignation
- PIAS 3
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Sujet
- Rabbit Anti-PIAS 3 Polyclonal Antibody,PIAS3, E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3,PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of PIAS3 have been identified, but the full-length nature of some of these variants has not been determined.,E3 SUMO-protein ligase PIAS3
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Poids moléculaire
- observerd band 68kDa
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ID gène
- 10401
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UniProt
- Q9Y6X2
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Pathways
- Signalistation JAK/STAT
Antigène
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