PTK6 anticorps (pTyr447)

N° du produit ABIN7223792

Cet anticorps Lapin Polyclonal détecte spécifiquement PTK6 dans WB, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PTK6 anticorps (pTyr447) (ABIN7223792)

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PTK6 anticorps

Épitope: pTyr447

Fonction: Brk (phospho Tyr447) Polyclonal Antibody

Specificité: Phospho-Brk (Y447) Polyclonal Antibody detects endogenous levels of Brk protein only when phosphorylated at Y447.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Brk Phospho-Tyr447

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PTK6

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Autre désignation: Brk

Sujet: Rabbit Anti-Brk (phospho Tyr447) Polyclonal Antibody,PTK6, BRK, Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK,The protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.,Protein-tyrosine kinase 6

Poids moléculaire: observerd band 50kDa

ID gène: 5753

UniProt: Q13882