RAP1A anticorps

N° du produit ABIN7230934

Cet anticorps anti-RAP1A est un anticorps Lapin Polyclonal détectant RAP1A dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RAP1A anticorps (ABIN7230934)

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAP1A anticorps

Fonction: RAP1A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RAP1A protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human RAP1A protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur RAP1A

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A

Sujet: Rabbit Anti-RAP1A Polyclonal Antibody,C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1,RAP1A encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of RAP1A have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.,RAP1A

Poids moléculaire: observerd band 20kDa

ID gène: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor