RGS1 anticorps (AA 90-170)

N° du produit ABIN7216822

Cet anticorps anti-RGS1 Polyclonal Lapin (ABIN7216822) détecte spécifiquement RGS1 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RGS1 anticorps (AA 90-170) (ABIN7216822)

Antigène: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RGS1 anticorps

Épitope: AA 90-170

Fonction: Rabbit Anti-RGS1 Polyclonal Antibody

Specificité: RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human RGS1 at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RGS1

Antigène: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Autre désignation: RGS1

Sujet: RGS1, 1R20, BL34, IER1, Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20RGS1 encodes a member of the regulator of G-protein signalling family. Regulator of G-protein signaling 1 is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Poids moléculaire: 22kD

ID gène: 5996

UniProt: Q08116

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events