LKB1 anticorps (pSer428)

N° du produit ABIN7224540

Cet anticorps anti-LKB1 est un anticorps Lapin Polyclonal détectant LKB1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour LKB1 anticorps (pSer428) (ABIN7224540)

Antigène: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LKB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LKB1 anticorps

Épitope: pSer428

Fonction: LKB1 (phospho Ser428) Polyclonal Antibody

Specificité: Phospho-LKB1 (S428) Polyclonal Antibody detects endogenous levels of LKB1 protein only when phosphorylated at S428.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human LKB1 Phospho-Ser428

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur LKB1

Antigène: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Autre désignation: LKB1

Sujet: Rabbit Anti-LKB1 (phospho Ser428) Polyclonal Antibody,STK11, LKB1, PJS, Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19,STK11 (serine/threonine kinase 11), which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been observed but have not been thoroughly characterized.,serine threonine-protein kinase STK11

Poids moléculaire: observerd band 65kDa

ID gène: 6794

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg