SGK1 anticorps (AA 350-430)

N° du produit ABIN7212186

L’anticorps anti-SGK1 Monoclonal Souris est utilisé pour la détection de SGK1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC et IF.

Aperçu rapide pour SGK1 anticorps (AA 350-430) (ABIN7212186)

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SGK1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 4D12

Détail du produit anti-SGK1 anticorps

Épitope: AA 350-430

Fonction: Mouse Anti-SGK1 Mouse Monoclonal Antibody (4D12)

Specificité: SGK1 protein detects endogenous levels of SGK1.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide of SGK1 at AA range of 350-430

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-200,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SGK1

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Autre désignation: SGK1

Sujet: SGK1SGK1 (serum/glucocorticoid regulated kinase 1) encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1.

Poids moléculaire: 45-60kD

ID gène: 6446

UniProt: O00141

Pathways: Signalisation MAPK, Signalisation Notch, Steroid Hormone Mediated Signaling Pathway