Stanniocalcin 2 anticorps (AA 170-250)
Aperçu rapide pour Stanniocalcin 2 anticorps (AA 170-250) (ABIN7231560)
Antigène
Voir toutes Stanniocalcin 2 (STC2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 170-250
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Fonction
- STC2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of STC2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human STC2 protein at AA range: 170-250
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Stanniocalcin 2 (STC2)
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Autre désignation
- STC2
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Sujet
- Rabbit Anti-STC2 Polyclonal Antibody,Stanniocalcin-related protein, STC-related protein, STCRP,STC2 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of STC2 is induced by estrogen and altered in some breast cancers.,STC2
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Poids moléculaire
- observerd band 33kDa
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ID gène
- 8614
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UniProt
- O76061
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Pathways
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
Antigène
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