Transportin 1 anticorps

N° du produit ABIN7231862

L’anticorps Lapin Polyclonal anti-Transportin 1 a été validé pour WB et ELISA. Il convient pour détecter Transportin 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Transportin 1 anticorps (ABIN7231862)

Antigène: Transportin 1 (TNPO1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Transportin 1 anticorps

Fonction: TNPO1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TNPO1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human TNPO1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: TNPO1

Sujet: Rabbit Anti-TNPO1 Polyclonal Antibody,Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein, MIP,TNPO1 (Transportin 1) is a Protein Coding gene. Diseases associated with TNPO1 include Hiv-1 and Dementia, Frontotemporal. Among its related pathways are Development_TGF-beta receptor signaling and CDK-mediated phosphorylation and removal of Cdc6. TNPO1 encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of TNPO1 results in two transcript variants encoding different proteins.,TNPO1

Poids moléculaire: observerd band 98kDa

ID gène: 3842

UniProt: Q92973

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events