BMP4 anticorps
Aperçu rapide pour BMP4 anticorps (ABIN7265898)
Antigène
Voir toutes BMP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- BMP4 Rabbit mAb
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Réactivité croisée
- Humain
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human BMP4
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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Autre désignation
- BMP4
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Sujet
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016],BMP2B, BMP2B1, MCOPS6, OFC11, ZYME,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytokines,ESC Pluripotency and Differentiation,Growth factors,Immunology & Inflammation,NF-kB Signaling Pathway,Signal Transduction,Stem Cells,TGF-b-Smad Signaling Pathway,TGF-b-Smad Signaling Pathway_Ligands,Wnt/β-Catenin Signaling Pathway,BMP4
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Poids moléculaire
- 47kDa
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ID gène
- 652
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UniProt
- P12644
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Pathways
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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