CDKN2C anticorps

N° du produit ABIN7266611

L’anticorps anti-CDKN2C Monoclonal Lapin est utilisé pour la détection de CDKN2C dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour CDKN2C anticorps (ABIN7266611)

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDKN2C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CDKN2C anticorps

Fonction: CDKN2C/p18-INK4C Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human CDKN2C/p18-INK4C

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CDKN2C

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Autre désignation: CDKN2C

Sujet: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],INK4C, p18, p18-INK4C,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,Tumor suppressors,CDKN2C

Poids moléculaire: 15kDa

ID gène: 1031

UniProt: P42773

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases