CDKN2C anticorps (AA 113-139)

N° du produit ABIN3030649

Détail du produit anti-CDKN2C anticorps

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Épitope: AA 113-139

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 113-139 from the human protein was used as the immunogen for this CDKN2C antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CDKN2C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CDKN2C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CDKN2C

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Autre désignation: CDKN2C (CDKN2C Produits)

Synonymes: anticorps CDKN2C, anticorps p18, anticorps ink4c, anticorps p18-ink4c, anticorps INK4C, anticorps p18-INK4C, anticorps C77269, anticorps INK4c, anticorps INK4d, anticorps p18INK4c, anticorps cyclin dependent kinase inhibitor 2C, anticorps cyclin-dependent kinase inhibitor 2C, anticorps cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), anticorps CDKN2C, anticorps cdkn2c, anticorps Cdkn2c

Sujet: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

UniProt: P42773

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases