DCUN1D1 anticorps (AA 15-70)

N° du produit ABIN7266719

Détail du produit anti-DCUN1D1 anticorps

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Épitope: AA 15-70

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCUN1D1 est non-conjugé

Application: Western Blotting (WB)

Fonction: DCUN1D1 Rabbit pAb

Séquence: FMIFTQSSEK TAVSCLSQND WKLDVATDNF FQNPELYIRE SVKGSLDRKK LEQLYN

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 15-70 of human DCUN1D1 (NP_065691.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DCUN1D1

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Autre désignation: DCUN1D1 (DCUN1D1 Produits)

Synonymes: anticorps fd19a01, anticorps zgc:66414, anticorps wu:fd19a01, anticorps dcun1l1, anticorps rp42, anticorps sccro, anticorps scro, anticorps tes3, anticorps DCNL1, anticorps DCUN1L1, anticorps RP42, anticorps SCCRO, anticorps SCRO, anticorps Tes3, anticorps Rp42, anticorps pTes3, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae), anticorps DCN1-like protein 1, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog, anticorps defective in cullin neddylation 1 domain containing 1, anticorps dcun1d1, anticorps dcnl1, anticorps dcun1d1.L, anticorps DCUN1D1, anticorps Dcun1d1

Sujet: Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8 thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity.,DCUN1D1,DCNL1,DCUN1L1,RP42,SCCRO,SCRO,Tes3,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Ubiquitin,DCUN1D1

Poids moléculaire: 30kDa

ID gène: 54165

UniProt: Q96GG9