NLRP2 anticorps (AA 704-754)

N° du produit ABIN7448989

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP2 dans IHC et IF (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NLRP2 anticorps (AA 704-754) (ABIN7448989)

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NLRP2 anticorps

Épitope: AA 704-754

Fonction: Rabbit anti-NBS1 IHC Antibody, affinity purified

Homologie: Orangutan,Monkey,Gorilla,Chimpanzee,Olive baboon,Crab-eating macaque,Bornean orangutan,Primates,Angolan talapoin,Francois's leaf monkey,Northern white-cheeked gibbon,Agile gibbon,Siamang,Black-and-white colobus monkey

Purification: Affinity Purified

Immunogène: Between AA 704 and 754

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: NBS1

Sujet: Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.

ID gène: 4683

NCBI Accession: NP_002476

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome