NLRP2 anticorps (AA 704-754)

N° du produit ABIN7453736

Détail du produit anti-NLRP2 anticorps

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Épitope: AA 704-754

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-NBS1 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 704 and 754

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: NBS1 (NLRP2 Produits)

Synonymes: anticorps CLR19.9, anticorps NALP2, anticorps NBS1, anticorps PAN1, anticorps PYPAF2, anticorps NLRP2, anticorps E330007A02Rik, anticorps Nalp2, anticorps NLR family pyrin domain containing 2, anticorps NACHT, LRR and PYD domains-containing protein 2, anticorps NLR family pyrin domain containing 7, anticorps NLR family, pyrin domain containing 2, anticorps NLRP2, anticorps LOC100301026, anticorps LOC100387349, anticorps NLRP7, anticorps Nlrp2

Sujet: Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.

ID gène: 4683

NCBI Accession: NP_002476

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome