PILRA anticorps

N° du produit ABIN7269157

Détail du produit anti-PILRA anticorps

Antigène: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PILRA est non-conjugé

Application: Western Blotting (WB)

Fonction: PILRA Rabbit pAb

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human PILRA.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PILRA

Antigène: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Autre désignation: PILRA (PILRA Produits)

Synonymes: anticorps PILRA, anticorps FDF03, anticorps AV021745, anticorps RGD1562847, anticorps paired immunoglobin like type 2 receptor alpha, anticorps paired immunoglobulin-like type 2 receptor alpha, anticorps paired immunoglobin-like type 2 receptor alpha, anticorps PILRA, anticorps LOC489841, anticorps Pilra

Sujet: Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.,PILRA,FDF03,PILRA

Poids moléculaire: 34kDa

ID gène: 29992

UniProt: Q9UKJ1