PRDM9 anticorps

N° du produit ABIN7269501

Détail du produit anti-PRDM9 anticorps

Antigène: PRDM9 (PR Domain Containing 9 (PRDM9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM9 est non-conjugé

Application: Western Blotting (WB)

Fonction: PRDM9 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human PRDM9.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRDM9

Antigène: PRDM9 (PR Domain Containing 9 (PRDM9))

Autre désignation: PRDM9 (PRDM9 Produits)

Synonymes: anticorps PRDM9, anticorps ZNF436, anticorps MEISETZ, anticorps MSBP3, anticorps PFM6, anticorps PRMD9, anticorps ZNF899, anticorps BC012016, anticorps Dsbc1, anticorps G1-419-29, anticorps Meisetz, anticorps Rcr1, anticorps repro7, anticorps Prdm7, anticorps zgc:63970, anticorps XFDL141, anticorps zinc finger with KRAB and SCAN domains 7-like, anticorps PR/SET domain 9, anticorps PR domain containing 9, anticorps PR domain containing 9 L homeolog, anticorps PR/SET domain 7, anticorps ZKSCAN7L, anticorps PRDM9, anticorps Prdm9, anticorps prdm9, anticorps prdm9.L, anticorps PRDM7

Sujet: The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described.,PFM6, KMT8B, MSBP3, ZNF899, MEISETZ,PRDM9

Poids moléculaire: 103kDa

ID gène: 56979

UniProt: Q9NQV7