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PACSIN1 anticorps (AA 240-390)

PACSIN1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7269626
  • Antigène Voir toutes PACSIN1 Anticorps
    PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))
    Épitope
    • 11
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 240-390
    Reactivité
    • 27
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 24
    • 2
    • 2
    Lapin
    Clonalité
    • 28
    Polyclonal
    Conjugué
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PACSIN1 est non-conjugé
    Application
    • 28
    • 15
    • 15
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Fonction
    PACSIN1 Rabbit pAb
    Séquence
    KRLVFLKEVL LDIKRHLNLA ENSSYIHVYR ELEQAIRGAD AQEDLRWFRS TSGPGMPMNW PQFEEWNPDL PHTTTKKEKQ PKKAEGVALT NATGAVESTS QAGDRGSVSS YDRGQPYATE WSDDESGNPF GGSETNGGAN PFEDDSKGVR V
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human PACSIN1 (NP_065855.1).
    Isotype
    IgG
    Top Product
    Discover our top product PACSIN1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))
    Autre désignation
    PACSIN1 (PACSIN1 Produits)
    Synonymes
    anticorps MGC84055, anticorps sdpii, anticorps pacsin1, anticorps x-PACSIN2, anticorps fe25d06, anticorps wu:fe25d06, anticorps zgc:114042, anticorps PACSIN1, anticorps SDPI, anticorps A830061D09Rik, anticorps H74, anticorps mKIAA1379, anticorps syndapin, anticorps protein kinase C and casein kinase substrate in neurons 1, anticorps protein kinase C and casein kinase substrate in neurons 1 S homeolog, anticorps protein kinase C and casein kinase substrate in neurons 2, anticorps protein kinase C and casein kinase substrate in neurons 1b, anticorps PACSIN1, anticorps pacsin1.S, anticorps pacsin2, anticorps pacsin1b, anticorps Pacsin1
    Sujet
    Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT, this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis, this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity. Binds to membranes via its F-BAR domain and mediates membrane tubulation.,PACSIN1,SDPI,Signal Transduction,PACSIN1
    Poids moléculaire
    50kDa
    ID gène
    29993
    UniProt
    Q9BY11
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