PTPRK anticorps (AA 600-750)

N° du produit ABIN7269702

Détail du produit anti-PTPRK anticorps

Antigène: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Épitope: AA 600-750

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRK est non-conjugé

Application: Western Blotting (WB)

Fonction: PTPRK Rabbit pAb

Séquence: EGVDASLNET ATTITVLLRP AQAKGAPISA YQIVVEELHP HRTKREAGAM ECYQVPVTYQ NAMSGGAPYY FAAELPPGNL PEPAPFTVGD NRTYQGFWNP PLAPRKGYNI YFQAMSSVEK ETKTQCVRIA TKAAATEEPE VIPDPAKQTD R

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human PTPRK (NP_001129120.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPRK

Antigène: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Autre désignation: PTPRK (PTPRK Produits)

Synonymes: anticorps R-PTP-kappa, anticorps Rptpk, anticorps AI853699, anticorps PTPk, anticorps RPTPkappa, anticorps protein tyrosine phosphatase, receptor type K, anticorps protein tyrosine phosphatase, receptor type, K, anticorps PTPRK, anticorps Ptprk

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.,PTPRK,R-PTP-kappa,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PTPRK

Poids moléculaire: 162kDa/163kDa/164kDa

ID gène: 5796

UniProt: Q15262

Pathways: Cell-Cell Junction Organization