RASGRP2
Reactivité: Humain, Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB,1:200 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
RASGRP2
(RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
Autre désignation
RASGRP2
Sujet
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.,RASGRP2,CALDAG-GEFI,CDC25L,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,RASGRP2