Sema4a anticorps (AA 320-580)

N° du produit ABIN7270199

Détail du produit anti-Sema4a anticorps

Antigène: Sema4a (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))

Épitope: AA 320-580

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sema4a est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: SEMA4A Rabbit pAb

Séquence: IYAVFTSQWQ VGGTRSSAVC AFSLLDIERV FKGKYKELNK ETSRWTTYRG PETNPRPGSC SVGPSSDKAL TFMKDHFLMD EQVVGTPLLV KSGVEYTRLA VETAQGLDGH SHLVMYLGTT TGSLHKAVVS GDSSAHLVEE IQLFPDPEPV RNLQLAPTQG AVFVGFSGGV WRVPRANCSV YESCVDCVLA RDPHCAWDPE SRTCCLLSAP NLNSWKQDME RGNPEWACAS GPMSRSLRPQ SRPQIIKEVL AVPNSILELP C

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 320-580 of human SEMA4A (NP_071762.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Sema4a

Antigène: Sema4a (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))

Autre désignation: SEMA4A (Sema4a Produits)

Synonymes: anticorps SEMA4A, anticorps CORD10, anticorps RP35, anticorps SEMAB, anticorps SEMB, anticorps AI132332, anticorps SemB, anticorps Semab, anticorps semaphorin 4A, anticorps sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A, anticorps SEMA4A, anticorps sema4a, anticorps Sema4a

Sujet: This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,SEMA4A,CORD10,RP35,SEMAB,SEMB,Neuroscience,Cardiovascular,Angiogenesis,SEMA4A

Poids moléculaire: 69kDa/83kDa

ID gène: 64218

UniProt: Q9H3S1