SQSTM1 anticorps (pSer349)
Aperçu rapide pour SQSTM1 anticorps (pSer349) (ABIN7270206)
Antigène
Voir toutes SQSTM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer349
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Fonction
- Phospho-SQSTM1/p62-S349 Rabbit pAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Phosphorylated Antibodies
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Purification
- Affinity purification
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Immunogène
- A phospho specific peptide corresponding to residues surrounding S349 of human SQSTM1/p62
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Autre désignation
- SQSTM1
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Sujet
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.,SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,Mitochondrial Control of Autophagy,SQSTM1
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Poids moléculaire
- 38kDa/47kDa
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ID gène
- 8878
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UniProt
- Q13501
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Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
Antigène
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