STAT5B anticorps
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- Antigène Voir toutes STAT5B Anticorps
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp STAT5B est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Fonction
- [KO Validated] STAT5B Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Classe de qualité
- KO Validated
- Immunogène
- A synthesized peptide derived from human STAT5B.
- Isotype
- IgG
- Top Product
- Discover our top product STAT5B Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
- Autre désignation
- STAT5B (STAT5B Produits)
- Synonymes
- anticorps STAT5, anticorps stat5, anticorps STAT5A, anticorps STAT5B, anticorps signal transducer and activator of transcription 5B, anticorps signal transducer and activator of transcription 5B S homeolog, anticorps Signal transducer and activator of transcription 5B, anticorps STAT5B, anticorps Stat5b, anticorps stat5b.S, anticorps LOC490969, anticorps sta5b, anticorps LOC100566752, anticorps LOC100052954
- Sujet
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008],STAT5,STAT5B,Cancer,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Signal Transduction,Transcription Factors,STAT5B
- Poids moléculaire
- 90kDa
- ID gène
- 6777
- UniProt
- P51692
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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