SNTA1 anticorps

N° du produit ABIN7270692

Détail du produit anti-SNTA1 anticorps

Antigène: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNTA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: Syntrophin alpha 1 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human Syntrophin alpha 1.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SNTA1

Antigène: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Autre désignation: Syntrophin alpha 1 (SNTA1 Produits)

Synonymes: anticorps SNTA1, anticorps MGC147484, anticorps AW228934, anticorps Snt1, anticorps LQT12, anticorps SNT1, anticorps TACIP1, anticorps dJ1187J4.5, anticorps syntrophin alpha 1, anticorps syntrophin, alpha 1 L homeolog, anticorps syntrophin, alpha 1, anticorps syntrophin, acidic 1, anticorps SNTA1, anticorps snta1.L, anticorps snta1, anticorps Snta1

Sujet: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013],LQT12, SNT1, TACIP1, dJ1187J4.5,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,Syntrophin alpha 1

Poids moléculaire: 54kDa

ID gène: 6640

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development