TMEM2 anticorps

N° du produit ABIN7270962

Détail du produit anti-TMEM2 anticorps

Antigène: TMEM2 (Transmembrane Protein 2 (TMEM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM2 est non-conjugé

Application: Western Blotting (WB)

Fonction: TMEM2 Rabbit pAb

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human TMEM2.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TMEM2

Antigène: TMEM2 (Transmembrane Protein 2 (TMEM2))

Autre désignation: TMEM2 (TMEM2 Produits)

Synonymes: anticorps 3110012M15Rik, anticorps mKIAA1412, anticorps transmembrane protein 2, anticorps tmem2, anticorps TMEM2, anticorps Tmem2

Sujet: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017],TMEM2,Cell Biology & Developmental Biology,TMEM2

ID gène: 23670

UniProt: Q9UHN6