Vcpip1 anticorps (AA 923-1222)

N° du produit ABIN7271285

Détail du produit anti-Vcpip1 anticorps

Antigène: Vcpip1 (Valosin Containing Protein (p97)/p47 Complex Interacting Protein 1 (Vcpip1))

Épitope: AA 923-1222

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vcpip1 est non-conjugé

Application: Western Blotting (WB)

Fonction: VCPIP1 Rabbit pAb

Séquence: VFYSIMKKTM GMADGKHCTF PHLPGKTFVY NASEDRLELC VDAAGHFPIG PDVEDLVKEA VSQVRAEATT RSRESSPSHG LLKLGSGGVV KKKSEQLHNV TAFQGKGHSL GTASGNPHLD PRARETSVVR KHNTGTDFSN SSTKTEPSVF TASSSNSELI RIAPGVVTMR DGRQLDPDLV EAQRKKLQEM VSSIQASMDR HLRDQSTEQS PSDLPQRKTE VVSSSAKSGS LQTGLPESFP LTGGTENLNT ETTDGCVADA LGAAFATRSK AQRGNSVEEL EEMDSQDAEM TNTTEPMDHS

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 923-1222 of human VCPIP1 (NP_079330.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Vcpip1

Antigène: Vcpip1 (Valosin Containing Protein (p97)/p47 Complex Interacting Protein 1 (Vcpip1))

Autre désignation: VCPIP1 (Vcpip1 Produits)

Synonymes: anticorps VCPIP1, anticorps vcip135, anticorps DUBA3, anticorps VCIP135, anticorps 4932442A08, anticorps 5730421J18Rik, anticorps 5730538E15Rik, anticorps mKIAA1850, anticorps Vcip135, anticorps valosin containing protein interacting protein 1, anticorps valosin containing protein (p97)/p47 complex interacting protein 1, anticorps VCPIP1, anticorps vcpip1, anticorps Vcpip1

Sujet: Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER (By similarity. Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.,VCPIP1,DUBA3,VCIP135,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,VCPIP1

Poids moléculaire: 134kDa

ID gène: 80124

UniProt: Q96JH7