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ZNF451 anticorps

ZNF451 Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7384122
  • Antigène Voir toutes ZNF451 Anticorps
    ZNF451 (Zinc Finger Protein 451 (ZNF451))
    Reactivité
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ZNF451 est non-conjugé
    Application
    • 18
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human ZNF451 (NP_001026794.1).
    Isotype
    IgG
    Top Product
    Discover our top product ZNF451 Anticorps primaire
  • Indications d'application
    WB 1:200-1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ZNF451 (Zinc Finger Protein 451 (ZNF451))
    Autre désignation
    ZNF451 (ZNF451 Produits)
    Synonymes
    anticorps COASTER, anticorps dJ417I1.1, anticorps 4930515K21Rik, anticorps 4933435G09Rik, anticorps AI596398, anticorps Kiaa0576-hp, anticorps Znf451, anticorps mKIAA1702, anticorps zinc finger protein 451, anticorps ZNF451, anticorps Zfp451
    Sujet
    ZNF451,COASTER,dJ417I1.1,E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.
    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 63 kDa/115 kDa/121 kDa

    ID gène
    26036
    UniProt
    Q9Y4E5
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