Caspase 8 anticorps

N° du produit ABIN7384425

L’anticorps Lapin Monoclonal anti-Caspase 8 a été validé pour WB. Il convient pour détecter Caspase 8 dans des échantillons de Hamster.

Aperçu rapide pour Caspase 8 anticorps (ABIN7384425)

Antigène: Caspase 8 (CASP8)

Reactivité: Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 8 est non-conjugé

Application: Western Blotting (WB)

Clone: R02-0D7

Détail du produit anti-Caspase 8 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Caspase 8

Antigène: Caspase 8 (CASP8)

Autre désignation: Caspase 8

Sujet: ALPS2B,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein,Apoptotic cysteine protease,Apoptotic protease Mch-5,Apoptotic protease Mch5,CAP4,CASP-8,CASP8,CASP8,Caspase 8,Caspase 8 apoptosis related cysteine peptidase,Caspase-8 subunit p10,CED 3,FADD Like ICE,FADD-homologous ICE/CED-3-like protease,FADD-like ICE,FLICE,FLJ17672,ICE-like apoptotic protease 5,MACH alpha 1/2/3 protein,MACH,MACH beta 1/2/3/4 protein,MCH5,MGC78473,MORT1 associated ced 3 homolog,MORT1-associated CED-3 homolog,OTTHUMP00000163717,OTTHUMP00000163720,OTTHUMP00000163724,OTTHUMP00000163725,OTTHUMP00000165062,OTTHUMP00000165063,OTTHUMP00000165064,OTTHUMP00000206552,OTTHUMP00000206582,Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 55kDa

ID gène: 841

UniProt: Q14790

Pathways: Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades