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Cofilin anticorps

Cet anticorps Lapin Monoclonal détecte spécifiquement Cofilin dans WB, IF et IHC (p). Il présente une réactivité envers Humain.
N° du produit ABIN7384433

Aperçu rapide pour Cofilin anticorps (ABIN7384433)

Antigène

Voir toutes Cofilin (CFL1) Anticorps
Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivité

  • 140
  • 92
  • 90
  • 7
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 138
  • 18
  • 2
  • 1
Lapin

Clonalité

  • 139
  • 19
Monoclonal

Conjugué

  • 78
  • 11
  • 10
  • 7
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Cofilin est non-conjugé

Application

  • 81
  • 61
  • 55
  • 47
  • 41
  • 41
  • 37
  • 28
  • 21
  • 13
  • 12
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

R06-2C0
  • Purification

    Affinity Purified

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

    Restrictions

    For Research Use only
  • Concentration

    300 μg/mL

    Buffer

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    Autre désignation

    Cofilin

    Sujet

    18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18,Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility,cytokinesis,and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity,also causing translocation from the nucleus to the cytoplasm.

    Poids moléculaire

    Observed_MW: 19kDa

    Calculated_MW: 19kDa

    ID gène

    1072

    UniProt

    P23528

    Pathways

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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