CHEK2 anticorps (AA 475-525)
Aperçu rapide pour CHEK2 anticorps (AA 475-525) (ABIN7448477)
Antigène
Voir toutes CHEK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 475-525
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Fonction
- Rabbit anti-Chk2 IHC Antibody, Affinity Purified
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Homologie
- Orangutan,Chimpanzee
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Purification
- Affinity Purified
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Immunogène
- Between AA 475 and 525
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Isotype
- IgG
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Indications d'application
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 500 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Autre désignation
- Chk2
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Sujet
- Background: Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425.
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ID gène
- 11200
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NCBI Accession
- NP_009125
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UniProt
- O96017
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Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire
Antigène
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