RNF40 anticorps (AA 540-590)

N° du produit ABIN7448780

Détail du produit anti-RNF40 anticorps

Antigène: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Épitope: AA 540-590

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF40 est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: Rabbit anti-RNF40 IHC Antibody, Affinity Purified

Homologie: Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 540 and 590

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RNF40

Antigène: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Autre désignation: RNF40 (RNF40 Produits)

Synonymes: anticorps AI848422, anticorps mKIAA0661, anticorps BRE1B, anticorps RBP95, anticorps STARING, anticorps ring finger protein 40, anticorps RNF40, anticorps Rnf40

Sujet: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 40 (RNF40) is a member of the RING type E3 ubiquitin ligases. RNF40 forms a complex with RNF20 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RN40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.

ID gène: 9810

NCBI Accession: NP_055586

UniProt: O75150