MAPKAP1 anticorps (C-Term)

N° du produit ABIN7448795

L’anticorps Lapin Polyclonal anti-MAPKAP1 a été validé pour IHC. Il convient pour détecter MAPKAP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour MAPKAP1 anticorps (C-Term) (ABIN7448795)

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MAPKAP1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-Sin1 IHC Antibody, Affinity Purified

Homologie: Rat,Chicken,Turkey,Sheep,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Tasmanian devil,Crab-eating macaque,Zebra finch,Small-eared galago,Chinese hamster,Naked mole rat,Gray short-tailed opossum,Thirteen-lined ground squirrel,West Indian ocean coelacanth,Little brown bat,Duckbill platypus

Purification: Affinity Purified

Immunogène: Between AA 470 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MAPKAP1

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Autre désignation: Sin1

Sujet: Background: Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling.

ID gène: 79109

NCBI Accession: NP_001006618

UniProt: Q9BPZ7

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events