Topo IIalpha (C-Term) anticorps
Aperçu rapide pour Topo IIalpha (C-Term) anticorps (ABIN7448837)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Rabbit anti-Topo II Alpha IHC Antibody, Affinity Purified
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Homologie
- Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Northern white-cheeked gibbon
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Purification
- Affinity Purified
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Immunogène
- Between AA 1500 and C-term
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Isotype
- IgG
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Indications d'application
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Topo IIalpha
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Autre désignation
- Topo II Alpha
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Sujet
- Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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ID gène
- 7153
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NCBI Accession
- NP_001058
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UniProt
- P11388
Antigène
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