Cet anticorps anti-Topo IIalpha Monoclonal Lapin (Clone BLR358N) (ABIN7795795) détecte spécifiquement Topo IIalpha dans WB, IHC et ICC.
L’anticorps est réactif avec des échantillons de Humain et Souris.
Reactivité: Humain
WB, ELISA, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1000 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
2 - 8 °C
Date de péremption
12 months
Antigène
Topo IIalpha
Autre désignation
Topo II Alpha
Sujet
Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.