Topo IIalpha (C-Term) anticorps

N° du produit ABIN7454588

Cet anticorps anti-Topo IIalpha Polyclonal Lapin (ABIN7454588) détecte spécifiquement Topo IIalpha dans WB, IHC (fp) et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Topo IIalpha (C-Term) anticorps (ABIN7454588)

Antigène: Topo IIalpha

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Détail du produit

Épitope: C-Term

Fonction: Rabbit anti-Topo II Alpha Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1500 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:30,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: Topo IIalpha

Autre désignation: Topo II Alpha

Sujet: Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.

ID gène: 7153

NCBI Accession: NP_001058

UniProt: P11388