L’anticorps anti-Topo IIalpha Monoclonal Lapin est utilisé pour la détection de Topo IIalpha dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et ICC.
Reactivité: Humain
WB, ELISA, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000
Restrictions
For Research Use only
Format
Liquid
Concentration
500 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
2 - 8 °C
Date de péremption
12 months
Antigène
Topo IIalpha
Autre désignation
Topo II Alpha
Sujet
Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.