TRAFD1 anticorps (AA 1-50)

N° du produit ABIN7450253

Détail du produit anti-TRAFD1 anticorps

Antigène: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Épitope: AA 1-50

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAFD1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-FLN29 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TRAFD1

Antigène: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Autre désignation: FLN29 (TRAFD1 Produits)

Synonymes: anticorps MGC80116, anticorps fln29, anticorps MGC89491, anticorps TRAFD1, anticorps 1110008K06Rik, anticorps Fln29, anticorps FLN29, anticorps TRAF-type zinc finger domain containing 1, anticorps TRAF-type zinc finger domain containing 1 L homeolog, anticorps TRAF-type zinc finger domain-containing protein 1, anticorps TRAF type zinc finger domain containing 1, anticorps TRAFD1, anticorps trafd1.L, anticorps trafd1, anticorps trad1, anticorps Trafd1

Sujet: Background: FLN29 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. FLN29 may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation It may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) [taken from the Universal Protein Resource (UniProt) O14545].

ID gène: 10906

NCBI Accession: NP_001137378

UniProt: O14545