PPFIBP1 anticorps (AA 175-225)

N° du produit ABIN7450418

Détail du produit anti-PPFIBP1 anticorps

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Épitope: AA 175-225

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPFIBP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Liprin beta 1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PPFIBP1

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Autre désignation: Liprin beta 1 (PPFIBP1 Produits)

Synonymes: anticorps liprin-beta-1, anticorps L2, anticorps SGT2, anticorps hSGT2, anticorps hSgt2p, anticorps 4632409B19Rik, anticorps AW214454, anticorps AW261454, anticorps PPFIA binding protein 1, anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1), anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog, anticorps Ppfibp1, anticorps ppfibp1, anticorps ppfibp1.S, anticorps PPFIBP1

Sujet: Background: Liprin beta 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. Liprin beta 1 was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiments demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2 [taken from NCBI Entrez Gene (Gene ID: 8496)].

ID gène: 8496

NCBI Accession: NP_803193

UniProt: Q86W92