Stanniocalcin 2 anticorps (AA 252-302)

N° du produit ABIN7450781

L’anticorps Lapin Polyclonal anti-Stanniocalcin 2 a été validé pour WB et IP. Il convient pour détecter Stanniocalcin 2 dans des échantillons de Humain.

Aperçu rapide pour Stanniocalcin 2 anticorps (AA 252-302) (ABIN7450781)

Antigène: Stanniocalcin 2 (STC2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Stanniocalcin 2 anticorps

Épitope: AA 252-302

Fonction: Rabbit anti-Stanniocalcin 2 Antibody, Affinity Purified

Homologie: Mouse,Rat,Orangutan

Purification: Affinity Purified

Immunogène: between AA 252 and 302

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: Stanniocalcin 2

Sujet: Background: Stanniocalcin 2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. Stanniocalcin 2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and is altered in some breast cancers [taken from NCBI Entrez Gene (GeneID: 8614)].

ID gène: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome