MYO5B anticorps (AA 50-100)

N° du produit ABIN7451161

Détail du produit anti-MYO5B anticorps

Antigène: MYO5B (Myosin VB (MYO5B))

Épitope: AA 50-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO5B est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-MYO5B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 50 and 100

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451161 has not performed satisfactorily when used for WB of MYO5B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO5B.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MYO5B

Antigène: MYO5B (Myosin VB (MYO5B))

Autre désignation: MYO5B (MYO5B Produits)

Synonymes: anticorps AI661750, anticorps mKIAA1119, anticorps Myr6, anticorps myosin VB, anticorps myosin Vb, anticorps MYO5B, anticorps Myo5b

Sujet: Background: Myosin 5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. MYO5B is required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Also, together with RAB11A, MYO5B participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A it participates in epithelial cell polarization. Together with RAB25 MYO5B regulates transcytosis [taken from the Universal Protein Resource (UniProt) Q9ULV0].

ID gène: 4645

UniProt: Q9ULV0