MYO5B anticorps (N-Term)

N° du produit ABIN966630

Détail du produit anti-MYO5B anticorps

Antigène: MYO5B (Myosin VB (MYO5B))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO5B est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human Myosin-5B (Myosin Vb)

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: This antibody is stored in PBS, 0.01% sodium azide and 50% glycerol.

Stock: -20 °C

Références pour anticorps anti-MYO5B (ABIN966630)

Szperl, Golachowska, Bruinenberg, Prekeris, Thunnissen, Karrenbeld, Dijkstra, Hoekstra, Mercer, Ksiazyk, Wijmenga, Wapenaar, Rings, van IJzendoorn: "Functional characterization of mutations in the myosin Vb gene associated with microvillus inclusion disease." dans: Journal of pediatric gastroenterology and nutrition, Vol. 52, Issue 3, pp. 307-13, (2011) (PubMed).

Détails sur MYO5B

Antigène: MYO5B (Myosin VB (MYO5B))

Autre désignation: MYO5B (MYO5B Produits)

Synonymes: anticorps AI661750, anticorps mKIAA1119, anticorps Myr6, anticorps myosin VB, anticorps myosin Vb, anticorps MYO5B, anticorps Myo5b

Sujet: MYO5B(Myosin-5B)(Myosin Vb)interacts with RAB11FIP2. MYO5B(Myosin-5B)(Myosin Vb) has a role in in glutamate receptor GluR1 trafficking. The myosin Vb functions in traffic between peripheral and pericentrosomal compartments. The protein contains 1 dilute domain and 6 IQ domains. It also contains 1 myosin head-like domain. The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament