RC3H1 anticorps (C-Term)

N° du produit ABIN7451565

Détail du produit anti-RC3H1 anticorps

Antigène: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RC3H1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Roquin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1075 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RC3H1

Antigène: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Autre désignation: Roquin (RC3H1 Produits)

Synonymes: anticorps RNF198, anticorps ROQUIN, anticorps RC3H1, anticorps si:dkey-192m14.4, anticorps 5730557L09Rik, anticorps Gm551, anticorps N28103, anticorps mKIAA2025, anticorps RGD1563512, anticorps rc3h1, anticorps ring finger and CCCH-type domains 1, anticorps ring finger and CCCH-type domains 1a, anticorps ring finger and CCCH-type zinc finger domains 1, anticorps RING CCCH (C3H) domains 1, anticorps ring finger and CCCH-type domains 1 L homeolog, anticorps RC3H1, anticorps rc3h1a, anticorps Rc3h1, anticorps rc3h1.L

Sujet: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Roquin is a member of the RING type E3 ubiquitin ligases. Roquin possesses a CCCH zinc-finger found in RNA-binding proteins and is implicated to play a role in the development of autoimmune disease.

ID gène: 149041

NCBI Accession: NP_742068

UniProt: Q5TC82

Pathways: Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation