MAP2K4 anticorps (AA 349-399)

N° du produit ABIN7451876

L’anticorps Lapin Polyclonal anti-MAP2K4 a été validé pour WB et IP. Il convient pour détecter MAP2K4 dans des échantillons de Humain et Souris.

Aperçu rapide pour MAP2K4 anticorps (AA 349-399) (ABIN7451876)

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K4 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MAP2K4 anticorps

Épitope: AA 349-399

Fonction: Rabbit anti-MKK4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 349 and 399

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MAP2K4

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Autre désignation: MKK4

Sujet: Background: MAPKK4 (mitogen-activated protein kinase kinase 4) is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. MAPKK4 is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. Studies in knockout mice suggest that MAPKK4 mediates survival signals in T cell development. It may also be important to liver organogenesis.[taken from NCBI Entrez Gene (GeneID: 6416)].

ID gène: 6416

NCBI Accession: NP_003001

UniProt: P45985

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling