SMARCAL1 anticorps (AA 904-954)
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- Antigène Voir toutes SMARCAL1 Anticorps
- SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))
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Épitope
- AA 904-954
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMARCAL1 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Fonction
- Rabbit anti-SMARCAL1 Antibody, Affinity Purified
- Homologie
- Bovine
- Purification
- Affinity Purified
- Immunogène
- between AA 904 and 954
- Isotype
- IgG
- Top Product
- Discover our top product SMARCAL1 Anticorps primaire
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- Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))
- Autre désignation
- SMARCAL1 (SMARCAL1 Produits)
- Synonymes
- anticorps SMARCAL1, anticorps im:7145331, anticorps si:ch211-239d11.1, anticorps harp, anticorps hharp, anticorps 6030401P21Rik, anticorps AI851716, anticorps Mharp, anticorps HARP, anticorps HHARP, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog, anticorps SMARCAL1, anticorps smarcal1, anticorps Smarcal1, anticorps smarcal1.L
- Sujet
- Background: The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAL1 is a member of the SNF2 family. SMARCAL1 is also known as human hep-related protein (HARP) due to its sequence identity with the E. coli RNA polymerase-binding protein HepA. It has been determined that mutations in SMARCAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal-recessive disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction, facial dysmorphism, and T-cell immunodeficiency. The pleiotropic characteristics of SIOD indicate an important role for SMARCAL1 in the regulation of multiple genes that influence the proliferation of chondrocytes, lymphocytes, and spermatozytes, as well as the development of cardiomyocytes and vascular homeostasis.
- ID gène
- 50485
- NCBI Accession
- NP_054859
- UniProt
- Q9NZC9
- Pathways
- Embryonic Body Morphogenesis
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