XPC anticorps (AA 890-940)

N° du produit ABIN7452171

Cet anticorps anti-XPC Polyclonal Lapin (ABIN7452171) détecte spécifiquement XPC dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour XPC anticorps (AA 890-940) (ABIN7452171)

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPC est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-XPC anticorps

Épitope: AA 890-940

Fonction: Rabbit anti-XPC Antibody, Affinity Purified

Homologie: Dog,Orangutan,Monkey,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogène: between AA 890 and 940

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur XPC

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Autre désignation: XPC

Sujet: Background: Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA.

ID gène: 7508

NCBI Accession: NP_004619

UniProt: Q01831

Pathways: Signalisation p53, Réparation de l'ADN