NCOR2 anticorps (AA 1925-1975)

N° du produit ABIN7452437

L’anticorps anti-NCOR2 Polyclonal produit chez le Lapin a été validé pour IP. Il convient pour la détection de NCOR2 dans des échantillons provenant de Humain. }

Aperçu rapide pour NCOR2 anticorps (AA 1925-1975) (ABIN7452437)

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR2 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-NCOR2 anticorps

Épitope: AA 1925-1975

Fonction: Rabbit anti-SMRT Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1925 and 1975

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SMRT antibody ABIN7452053.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NCOR2

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Autre désignation: SMRT

Sujet: Background: SMRT (silencing mediator of retinoid and thyroid hormone receptor) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. SMRT mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.

ID gène: 9612

UniProt: Q9Y618

Pathways: Signalisation Notch, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha