TAB2 anticorps (AA 300-350)

N° du produit ABIN7452448

Cet anticorps Lapin Polyclonal détecte spécifiquement TAB2 dans IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TAB2 anticorps (AA 300-350) (ABIN7452448)

Antigène: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAB2 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-TAB2 anticorps

Épitope: AA 300-350

Fonction: Rabbit anti-TAB2 Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-TAB2 antibody ABIN7452084.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TAB2

Antigène: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Autre désignation: TAB2

Sujet: Background: TAB2 (TGF-beta-activated kinase 1and MAP3K7-binding protein 2) functions as an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. TAB2 forms a kinase complex with TRAF6, MAP3K7 and TAB1, and thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts [taken from NCBI Entrez Gene (GeneID: 23118)].

ID gène: 23118

NCBI Accession: NP_055908

UniProt: Q9NYJ8

Pathways: TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway