XPC anticorps (AA 825-875)

N° du produit ABIN7452477

Cet anticorps anti-XPC Polyclonal Lapin (ABIN7452477) détecte spécifiquement XPC dans IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour XPC anticorps (AA 825-875) (ABIN7452477)

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPC est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-XPC anticorps

Épitope: AA 825-875

Fonction: Rabbit anti-XPC Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 825 and 875

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-XPC antibody ABIN7452171.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur XPC

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Autre désignation: XPC

Sujet: Background: Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA.

ID gène: 7508

NCBI Accession: NP_004619

UniProt: Q01831

Pathways: Signalisation p53, Réparation de l'ADN