CAND1 anticorps (AA 600-650)

N° du produit ABIN7452494

L’anticorps Lapin Polyclonal anti-CAND1 a été validé pour IP. Il convient pour détecter CAND1 dans des échantillons de Humain.

Aperçu rapide pour CAND1 anticorps (AA 600-650) (ABIN7452494)

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAND1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-CAND1 anticorps

Épitope: AA 600-650

Fonction: Rabbit anti-CAND1 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: between AA 600 and 650

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CAND1

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Autre désignation: CAND1

Sujet: Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].

ID gène: 55832

NCBI Accession: NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization